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. 2021 Jan 6;51(2):231–238. doi: 10.1007/s00247-020-04921-9

Table 2.

Chest radiograph findings in pediatric patients with multisystem inflammatory syndrome in children (MIS-C) and coronavirus disease 2019 (COVID-19)

MIS-C (n=11) COVID-19 (n=16) P-value
Baseline chest radiograph normal, n (%) 7 (64%) 6 (38%) 0.25
Number of chest radiographs, mean (SD) 6.3 (5.1) 2.8 (2.6) 0.03
Day of most severe radiograph, mean (SD) 4.5 (2.3) 3.3 (3.6) 0.34
Severity score, mean (SD) 3.6 (1.4) 2.9 (2.4) 0.39
COVID-19 classification
 Typical, n (%) 2 (18%) 4 (25%) >0.99
 Indeterminate, n (%) 0 (0%) 8 (50%) <0.01
 Atypical, n (%) 9 (82%) 1 (6%) <0.01
 Negative, n (%) 0 (0%) 3 (19%) 0.25
Opacity, n (%)
 Consolidation only, n (%) 0 (0%) 0 (0%) >0.99
 Ground glass opacities only, n (%) 2 (18%) 8 (50%) 0.12
 Both, n (%) 8 (73%) 5 (31%) 0.05
 None, n (%) 1 (9%) 3 (19%) 0.62
Laterality of opacitiesa
 Right only, n (%) 0 (0%) 0 (0%) >0.99
 Left only, n (%) 0 (0%) 2 (15%) 0.49
 Bilateral, n (%) 10 (100%) 11 (85%) 0.49
Distribution of opacitiesa
 Peripheral, n (%) 4 (40%) 5 (38%) >0.99
 Central, n (%) 0 (0%) 2 (15%) 0.50
 Neither, n (%) 6 (60%) 6 (46%) 0.70
Predominance of opacitiesa
 Upper zone, n (%) 0 (0%) 0 (0%) >0.99
 Lower zone, n (%) 10 (100%) 5 (38%) <0.01
 Neither, n (%) 0 (0%) 8 (62%) <0.01
Pleural effusion, n (%) 9 (82%) 0 (0%) <0.01

Findings are based on the most severe radiograph. Bold values indicate statistical significance. SD standard deviation

an=13 for patients with COVID-19 and n=10 for patients with MIS-C; three patients with COVID-19 and one patient with MIS-C had no opacities by chest radiography