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. 2020 Dec 24;55:105–111. doi: 10.1016/j.breast.2020.12.009

Table 2.

Physician-assessed acute toxicity for effective treatment and intention to treat.

Acute toxicity for effective treatment
Acute toxicity for intention to treat
5-fraction schedule 15-fraction schedule 5-fraction schedule 15-fraction schedule
N 105 94 100 99
Breast pain 29 (27.6%) 47 (50.0%) 25 (25.0%) 51 (51.5%)
Fatigue 12 (11.4%) 37 (39.4%) 10 (10.0%) 39 (39.4%)
Breast edema 25 (23.8%) 44 (46.8%) 22 (22.0%) 47 (47.5%)
 Grade 1 24 (22.2%) 40 (42.6%) 21 (21.0%) 43 (43.4%)
 Grade 2 1 (1.0%) 4 (4.3%) 1 (1.0%) 4 (4.0%)
Dermatitis 61 (58.1%) 73 (77.7%) 57 (57.0%) 77 (77.8%)
 Grade 1 44 (40.7%) 54 (57.4%) 44 (44.0%) 54 (54.5%)
 Grade 2 17 (16.2%) 19 (20.2%) 13 (13.0%) 23 (23.2%)
Desquamation 15 (14.3%) 22 (23.4%) 12 (12.0%) 25 (25.3%)
 Grade 1 12 (11.1%) 17 (18.1%) 11 (11.0%) 18 (18.2%)
 Grade 2 3 (2.9%) 5 (5.3%) 1 (1.0%) 7 (7.1%)