Figure 7.
Lipidomic analysis of livers in the PKCβfl/fl and PKCβHep−/− mice on an HFD. Comparison of liver mass contents of TG (A) and individual molecular species of TG (B) in the liver samples of the HFD-fed PKCβHep−/− mice relative to the PKCβfl/fl mice. Mass content of lipids was determined by multidimensional mass spectrometric array analyses by comparing the peak intensity of each individual ion to that of the selected internal standards after correction for 13C isotopomer distribution differences as described in the Materials and methods section. Data are mean ± SE, n = 4, and ∗∗p < 0.001.