Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 23;11:617492. doi: 10.3389/fphys.2020.617492

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Langenbacher, Shimizu, Hsu, Zhao, Borges, Koehler and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Upregulated genes in MCU hearts reflect altered mitochondrial biology. (A, B) Dot plots of over-represented Biological Process (A) and Molecular Function (B) gene ontology terms in the set of genes that is significantly upregulated in MCU mutant hearts. The dot size indicates the number of genes associated with each term and the dot color indicates the significance of the enrichment (adjusted p-values). (C) Gene concept networks of the top 10 over-represented Biological Process gene ontology terms in the set of genes that is significantly upregulated in MCU mutants. The dot size indicates the number of genes associated with each term and dots representing genes are colored based on their fold-change [log2(fold-change)].