. 2020 Dec 8;47:100894. doi: 10.1016/j.dcn.2020.100894

Table 4.

Summary of hypothesized region definitions.

Hypothesized region(s)	Region definition	Direction hypothesized	Findings
General: Adversity
Ventromedial prefrontal cortex (vmPFC)	Areas s32, p32, 10 r from the HCP parcellation	Negative	Null
Subgenual anterior cingulate cortex (sgACC)	Area 25 from the HCP parcellation	Negative	Null
Lateral prefrontal cortex (lPFC)	Manually defined region-of-interest from Vijayakumar et al., 2014	Negative	General: Clusters within left anterior lPFC were negatively associated with adversity
Lateral prefrontal cortex (lPFC)		Negative	Dimensional: Left dorsal lPFC was negatively associated with neglect
Orbitofrontal cortex (OFC)	Lateral orbitofrontal or medial orbitofrontal labels within the Desikan-Killiany atlas	Unspecified	General: Null
Orbitofrontal cortex (OFC)		Unspecified	Dimensional: A cluster within right OFC was positively associated with abuse
Posterior cingulate cortex (PCC)/precuneus	Posterior cingulate, isthmmus cingulate, or precuneus labels within the Desikan-Killiany atlas	Unspecified	General: Null
Posterior cingulate cortex (PCC)/precuneus		Unspecified	Dimensional: Clusters within the PCC and left precuneus were negatively associated with abuse; a more posterior cluster within the left precuneus was negatively associated with neglect
Insula	Insula label within the Deskian-Killiany atlas	Unspecified	General: Null
Insula	Insula label within the Deskian-Killiany atlas	Unspecified	Dimensional: A cluster in left anterior insula was negatively associated with neglect
Dimensional: Abuse
Ventromedial prefrontal cortex (vmPFC)	Areas s32, p32, 10 r in the HCP parcellation	Unspecified	Null
Subgenual anterior cingulate cortex (sgACC)	Area 25 in the HCP parcellation	Unspecified	Null
Lateral prefrontal cortex (lPFC) within the frontoparietal network	Manually defined region-of-interest from Vijayakumar et al., 2014 AND within a parcel that is part of the frontoparietal community in the Gordon parcellation scheme	Unspecified	General: Left anterior lPFC clusters within the frontoparietal network were negatively associated with adversity
		Unspecified	Dimensional: Null
Dimensional: Neglect
Dorsal attention network	Within a parcel that is part of the dorsal attention (DA) community in the Gordon parcellation scheme	Negative	General: Left precentral gyrus was negatively associated with adversity; left inferior temporal gyrus was positively associated with adversity
Dorsal attention network		Negative	Dimensional: Clusters within the dorsal lPFC and intraparietal sulcus were negatively associated with neglect; clusters within the left precentral gyrus were negatively associated with abuse
Sensory and somatomotor networks	Within a parcel that is part of the visual (Vis), auditory (Aud), or somatomotor (SMh or SMm) communities in the Gordon parcellation scheme	Negative	General: Clusters within the visual network (right parahippocampal gyrus) were positively associated with adversity
Sensory and somatomotor networks		Negative	Dimensional: Clusters within the visual network were positively associated with neglect; more inferior regions within the visual network were positively associated with adversity and/or abuse. No clusters were identified within the auditory network. Clusters within somatomotor networks were negatively associated with abuse only. See section 3.1.5 for more on interactions.