Table 2.
Measurement | Fixed effects | Likelihood ratio χ2 | p | Estimate | 95% CI | t | df | p | |
---|---|---|---|---|---|---|---|---|---|
lower | upper | ||||||||
Learning | time | 10.50 | 0.001 | 0.002 | 0.001 | 0.003 | 4.27 | 248 | <0.001 |
group | 7.19 | 0.01 | −0.225 | −0.506 | 0.055 | −1.57 | 236 | 0.12 | |
time*group | 8.86 | 0.003 | −0.002 | −0.003 | −0.001 | −2.98 | 248 | <0.01 | |
Immediate recall | time | 7.41 | 0.01 | 0.002 | 0.001 | 0.003 | 3.44 | 247 | <0.001 |
group | 13.66 | <0.001 | −0.377 | −0.651 | −0.103 | −2.69 | 236 | <0.01 | |
time*group | 5.58 | 0.02 | −0.002 | −0.003 | −0.0003 | −2.36 | 247 | 0.02 | |
Delayed recall | time | 10.81 | 0.001 | 0.002 | 0.001 | 0.003 | 3.94 | 248 | <0.001 |
group | 14.07 | <0.001 | −0.354 | −0.618 | −0.091 | −2.63 | 236 | <0.01 | |
time*group | 6.67 | 0.01 | −0.002 | −0.003 | −0.001 | −2.58 | 248 | 0.01 | |
Recognition | time | 0.72 | 0.40 | 0.001 | −0.001 | 0.002 | 0.32 | 248 | 0.75 |
group | 14.23 | <0.001 | −0.502 | −0.815 | −0.189 | −3.13 | 236 | <0.01 | |
time*group | 0.81 | 0.37 | −0.001 | −0.002 | 0.001 | −0.89 | 248 | 0.37 | |
Left hippocampus | time | 0.38 | 0.54 | −0.004 | −0.11 | −0.17 | −0.06 | 141 | 0.96 |
group | 2.60 | 0.11 | −67.41 | −163.11 | 7.05 | −1.58 | 194 | 0.12 | |
time*group | 0.06 | 0.80 | −0.021 | −0.22 | 0.09 | −0.25 | 144 | 0.80 | |
Right hippocampus | time | 4.17 | 0.04 | −0.054 | −0.24 | 0.13 | −0.57 | 141 | 0.57 |
group | 0.68 | 0.41 | −39.52 | −137.1 | 58.1 | −0.79 | 194 | 0.43 | |
time*group | 0.17 | 0.68 | −0.043 | −0.25 | 0.16 | −0.41 | 141 | 0.68 | |
Left parahippocampal cortex | time | 2.19 | 0.14 | 0.000 | −0.0001 | 0.0002 | 0.52 | 143 | 0.60 |
group | 1.01 | 0.35 | −0.031 | −0.101 | 0.038 | −0.88 | 195 | 0.38 | |
time*group | 1.76 | 0.19 | −0.0001 | −0.0003 | 0.000 | −1.32 | 143 | 0.19 | |
Right parahippocampal cortex | time | 2.62 | 0.11 | 0.0001 | −0.000 | 0.0002 | 1.09 | 143 | 0.28 |
group | 5.50 | 0.02 | −0.063 | −0.12 | −0.005 | −2.13 | 195 | 0.035 | |
time*group | 4.06 | 0.04 | −0.0002 | −0.0003 | −0.000 | −2.02 | 143 | 0.045 | |
Left entorhinal cortex | time | 1.51 | 0.22 | 0.000 | −0.0002 | 0.0002 | −0.09 | 143 | 0.93 |
group | 0.42 | 0.52 | −0.024 | −0.105 | 0.057 | −0.58 | 195 | 0.56 | |
time*group | 0.26 | 0.61 | −0.000 | −0.0003 | 0.0002 | −0.51 | 143 | 0.61 | |
Right entorhinal cortex | time | 4.22 | 0.04 | −0.0002 | −0.0005 | −0.000 | −1.84 | 143 | 0.07 |
group | 0.41 | 0.52 | −0.034 | −0.122 | 0.055 | −0.74 | 195 | 0.46 | |
time*group | 1.10 | 0.29 | 0.0002 | −0.0001 | 0.0004 | 1.04 | 143 | 0.30 |
Estimates for sex, comp1, comp2, comp3 [and age for hippocampal volume] are not displayed.
Regression weights (column Estimate) are to be interpreted as the difference in z-scores [z], volume [mm3], or thickness [mm] between groups, days, or the interaction between them. Bold values indicate significance at p < 0.05.