Figure 3.

Correlation of LCN2 expression with immune infiltration level in cancers. (A) Correlation of LCN2 expression with infiltration level of immune cells by xCell in TCGA. Immune cells positively correlating with LCN2 expression in TCGA dataset were labeled in red, and immune cells negatively correlating with LCN2 expression in TCGA dataset were labeled in violet. (B) Correlation of LCN2 expression with immune infiltration level in BRCA, PRAD, and THCA. LCN2 expression has significant negative correlation with tumor purity, and significant positive correlation with infiltrating levels of B cell, CD8+ T cell, CD4+ T cell, macrophage, neutrophil, and dendritic cell. No relation with infiltrating levels of B cell and CD8+ T cell. *p < 0.05, **p < 0.01, and ***p < 0.001.