FIGURE 1.

Respiratory parameters. (a) The ratio of arterial oxygen partial pressure to fraction of inspired oxygen (P/F, kPa), (b) oxygenation index (OI), (c) alveolar–arterial gradient (AaG, kPa) before (basal value, BV), at established ARDS, and during 4 hours after administration of surfactant therapy (marked with an arrow head). Data are presented as mean ±SD. Statistical comparisons: α for poractant alfa and β for CHF5633 represent p < 0.001 and βi for CHF5633 represent p < 0.01 vs. Control