Figure 2.

Lgmn in xenograft model of OSCC. A, B, Active Lgmn labeled by LE28 (A), shown by in-gel fluorescence, and total Lgmn immunoreactivity (IR; B), shown by Western blotting of lysates from HSC-3 xenografts or control tongues. The gel from (A) was transferred to nitrocellulose and immunoblotted for total Lgmn levels (B). C, Densitometry of active and total Lgmn from A, B, respectively (n = 3–5, t₍₆₎ = 2.592, *p = 0.0411, when active Lgmn in normal mouse tongue and xenograft cancer is compared, and t₍₆₎ = 2.818, *p = 0.0304, when total Lgmn in normal mouse tongue xenograft cancer is compared, unpaired Student's t tests).