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. 2020 Oct 8;104(1):117–129. doi: 10.1093/biolre/ioaa186

Table 1.

Effects of anti-NEDL2 antibody microinjection into oocytes on fertilization, pronuclear formation, and embryo development in vitro.

Hours post-IVF Treatment
Parameters Control (n) NEDL2 AB (n)
21 h % of oocytes fertilized 92.8 ± 1.9 (219) 91.5 ± 1.9 (232)
% of oocytes formed pronucleus 96.0 ± 2.2 91.2 ± 2.2
% of oocytes fertilized but no pronucleus formed 4 ± 1.8a 12.9 ± 1.8b
# of spermatozoa penetrated oocyte 4.2 ± 0.2 4.1 ± 0.2
# of pronuclei in oocyte 4.2 ± 0.1a 2.8 ± 0.1b
% of monospermic fertilization 5.6 ± 1.6a 12.9 ± 1.6b
48 h % of oocytes cleaved 52.2 ± 8.4 (172) 55.7 ± 8.4 (154)
168 h % of blastocysts formed 14.2 ± 4.3 7.9 ± 4.3

a,bMeans with the column with different superscripts differ (P < 0.05).