Table 4.
Primary treatment | mpMRI score | PET score | PET/MRI score | Site of lesion | Consequences for choice of treatment |
---|---|---|---|---|---|
RP | 2 | 1 | 1 | Seminal vesicle | No |
RP | 2 | 3 | 3 | Seminal vesicle | No |
EBRT | 2 | 1 | 1 | Seminal vesicle | No |
RP+ePLND | 2 | 3 | 3 | LN, pelvic | No |
RP | 2 | 1 | 1 | LN - pelvic | Yes, EBRT field reduced |
RP+ePLND | 2 2 |
3 2 |
3 3 |
LN – pelvic LN - pelvic |
Yes, EBRT field extended |
RP+ePLND, sEBRT | 1 1 |
2 2 |
2 2 |
LN, other LN, other |
No |
EBRT | 2 1 1 |
3 3 3 |
3 3 3 |
LN, pelvic LN, pelvic LN, paraaortic |
Yes, systemic treatment due to paraaortic LN |
EBRT+ePLND | 2 | 3 | 3 | LN – paraaortic | No* |
RP+ePLND | 1 | 3 | 3 | Bone - pelvic | Yes, extended EBRT field |
RP+ePLND | 2 | 1 | 1 | Bone - pelvic | No |
Patients in bold were up-staged based on PET. *patient had multiple other lymph nodes with score 3 on both mpMRI and PET/MRI and overall score for the patient was not changed. RP, radical prostatectomy; EBRT, external beam radiation therapy; ePLND, extended pelvic lymph node dissection; sEBRT, salvage EBRT; LN, lymph node.