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. 2020 Dec 23;10:586019. doi: 10.3389/fonc.2020.586019

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Copyright © 2020 Zhou, Yan, Liu, Yin, Xu, Cheng, Jiang and Ren

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Subtype-specific genes and signaling pathways in diffuse glioma. (A, B) KEGG analysis of differentially expressed genes in subtypes C1 (A) and C3 (B). The size and color of the dots represent the number of genes and the range of P values, respectively. (C) A Venn diagram depicting overlapping immune-gene sets among the three subtypes. (D) t-SNE analysis showing the stratification based on the expression profile of subtype-specific genes in TCGA cohort. (E) The expression profile of 109 subtype-specific genes.