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Frequency of (a) CD3+ CD8+ T cells. (b) CD4+ T cells. (c) CD25+ FOXP3+ CD4+ Tregs in relation to early (I, II) versus late (III) stage of BC. Mann-Whitney U test was performed to access statistical significance. Bars represent standard deviation. A significant difference in the frequency of CD3+ CD8+ T cells was found between early and late tumor stages (P = 0.011).
