Table 1.
Patient demographics and disease characteristics.
| BC (n = 20) | BBL (n = 15) | HV (n = 20) | P | |
|---|---|---|---|---|
| Age in years (mean ± SD) | 50.6 ± 11.7 | 55.0 ± 13.7 | 64.3 ± 9.9 | 0.18 |
| HPV | ||||
| Positive | 4 | 0 | 0 | ND |
| Negative | 16 | 15 | 20 | |
| Percent lymphocyte subsets | ||||
| CD4+ Tregs (mean ± SD) | 4.39 ± 1.31 | 1.73 ±.74 | 1.73 ± .63 | 0.001 |
| CD8+ (mean ± SD) | 22.51 ± 5.51 | 23.93 ± 6.30 | 23.95 ± 8.08 | 0.8 |
| CD4+ (mean ± SD) | 43.16 ± 8.05 | 43.16 ± 7.39 | 40.17 ± 7.68 | 0.35 |
| Histology type, n (%) | ||||
| Carcinoma in situ | 1 (5.3%) | |||
| Invasive duct carcinoma | 14 (73.7%) | |||
| Invasive mammary carcinoma | 1 (5.3%) | |||
| Metaplastic carcinoma | 3 (15.8%) | |||
| Benign mammary lesion | 4 (33.3%) | |||
| Fibroadenoma | 3 (25.0%) | |||
| Fibrocystic changes | 1 (8.3%) | |||
| Benign ductal epithelial cells | 1 (8.3%) | |||
| Benign mastitis | 1 (8.3%) | |||
| Benign unspecified | 2 (16.7%) | |||
| Unknown | 1 | 3 | ||
| Tumor size | ||||
| <2 cm | 2 (10.5%) | 1 (11.1%) | ||
| 2−5 cm | 12 (63.2%) | 3 (33.3%) | 0.31 | |
| >5 cm | 5 (26.3%) | 5 (55.6%) | ||
| Unknown | 1 | 3 | ||
ND: not done because the group is <5; BBL: breast benign lesions; HV: healthy volunteers; SD: standard deviation.
P < 0.05 is significant.