Table 2.

Frequency of CD4+ Tregs and CD8+ T cells in BC patients according to age, HPV, and tumor characteristics.

	Item	n (%)	CD4+ T regs (mean ± SD)	P	CD8+ T cells (mean ± SD)	P
1.	Age in years			0.12		0.77
	<50	7 (35%)	3.77 ± 1.08		21.95 ± 6.42
	>50	8 (40%)	4.76 ± 1.62		20.40 ± 4.13
	Unknown	5 (25%)
2.	HPV			ND		ND
	Positive	4 (20%)	4.23 ± 1.10		22.57 ± 8.88
	Negative	16 (80%)	4.43 ± 1.39		22.49 ± 4.77
3.	Grade			ND		ND
	G1 & G2	16 (80%)	4.17 ± 1.35		22.08 ± 6.05
	G3	3 (15%)	5.04 ± .71		23.74 ± 2.33
	Unknown	1 (5%)
4.	Pathology			0.68		0.5
	IDC	14 (70%)	4.37 ± 1.40		22.60 ± 4.91
	Others	5 (25%)	4.14±1.10		21.63 ± 7.91
	Unknown	1 (5%)
5.	LN metastasis			0.19		0.1
	Positive	8 (40%)	4.12 ± 1.57		19.74 ± 3.98
	Negative	8 (40%)	4.77 ± .76		24.87 ± 7.06
	Unknown	4 (20%)
6.	Stage			0.79		0.01
	Early (I & II)	10 (50%)	4.52 ± 1.41		19.22 ± 4.33
	Advanced (III)	6 (30%)	4.32 ± .97		27.44 ± 5.35
	Unknown	4 (20%)
7.	ER			ND		ND
	Positive	13 (65%)	4.46 ± 1.40		22.85 ± 6.17
	Negative	4 (20%)	3.68 ± 1.24		20.57 ± 5.54
	Unknown	3 (15%)
8.	PR			0.16		0.19
	Positive	10 (50%)	4.74 ± 1.28		24.42 ± 5.76
	Negative	7 (35%)	3.61 ± 1.29		19.30 ± 5.14
	Unknown	3 (15%)
9.	HER2			ND		ND
	Positive	4 (20%)	4.04 ± 1.24		22.85 ± 4.94
	Negative	13 (65%)	5.06 ± 1.69		20.56 ± 9.23
	Unknown	3 (15%)
10.	Triple negative			ND		ND
	Yes	3 (15%)	3.17 ± .87		23.09 ± 2.78
	No	14 (70%)	4.51 ± 1.36		22.14 ± 6.49
	Unknown	3 (15%)

ND: not done because the group is <5; BBL: breast benign lesions; HV: healthy volunteers; SD: standard deviation.

P < 0.05 is significant.