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D-mannose decreased the number of TEM and TFH cells and increased the frequency of Treg cells in recipient mice in the cGVHD model. Frequency and numbers of recipient TEM (a-b), TFH (c-d) and Treg (e-f) cells in the mLN. Representative FACS plots of donor (CD45.2+) and recipient (CD45.2−) cells are shown on the left. Mean ± S.E.M of n = 4 per group compared with t tests. *: p < 0.05, **: p < 0.01
