TABLE 3.
Best- and Worst-Case Cost-effectiveness of Interventions for Increasing HPV Vaccination
| Interventions | Total Cost, $ | Incremental QALYs Gained Versus Next Best, n | Incremental Cost per QALY Gained Versus Next Best, $ | QALYs Gained Versus No Intervention, n | Cost per QALY Gained Versus No Intervention, $ |
|---|---|---|---|---|---|
| Worst-case costs | |||||
| QI visits | 97 283 | 42 | 2307 | 42 | 2307 |
| Reminder and recall | 1 734 190 | 33 | 50 366 | 75 | 23 228 |
| School-located vaccination | 3 797 821 | 162a | 22 817a | 204 | 18 586 |
| Best-case costs | |||||
| QI visits | 41 693 | 42 | 989 | 42 | 989 |
| Reminder and recall | 623 371 | 33 | 17 898 | 75 | 8349 |
| School-located vaccination | 2 279 682 | 162a | 10 213a | 204 | 11 156 |
| Worst-case effectiveness | |||||
| QI visits | 64 855 | 15 | 4388 | 15 | 4388 |
| Reminder and recall | 984 270 | 4 | 221 546 | 19 | 51 995 |
| School-located vaccination | 3 038 752 | 18a | 166 232a | 33 | 93 014 |
| Best-case effectiveness | |||||
| QI visits | 64 855 | 72 | 900 | 72 | 900 |
| Reminder and recall | 984 270 | 56 | 16 421 | 128 | 7688 |
| School-located vaccination | 3 038 752 | 219a | 13 610a | 291 | 10 459 |
Costs and QALYs discounted at 3% per year.
a
Indicates that school-located vaccination has dominance and extended dominance compared with reminder and recall intervention; comparisons were made to QI visits.