Table 1.
Lewy body count and severity based on the greatest density per 1 mm2 area
| Brain regions | Lewy body count | Severity† |
|---|---|---|
| Entorhinal cortex | 64 | +++ |
| Amygdala | 55 | +++ |
| Midfrontal cortex | 52 | +++ |
| Middle temporal cortex | 23 | +++ |
| Cingulate cortex | 20 | +++ |
| Basal ganglia | 18 | ++ |
| Inferior parietal lobule | 16 | ++ |
| Inferior orbital frontal cortex | 10 | ++ |
| Thalamus | 7 | ++ |
| Anterior temporal pole | 6 | ++ |
| Hippocampus (CA1 sector) | 6 | ++ |
| Substantia nigra | 2 | + |
| Hippocampus (dentate gyrus) | 0 | − |
| Cerebellum | 0 | − |
Graded as none (−), mild (+), moderate (++), and severe (+++).