Table 1.
Important parameters and the obtained results from assays for the plasmonic metasensor.
| Sensor device | Plasmonic metasensor [Current approach] | Plasmonic photothermal biosensor (Mujawar et al., 2020) | Gated graphene-enhanced FET based biosensor (Azzi et al., 2020) |
|---|---|---|---|
| Target | SARS-CoV-2 spike protein | SARS-CoV-2 spike protein | SARS-CoV-2 spike protein |
| LoD | ~4.2 fM | 0.22 pM | 1 fg/mL |
| Assay components | AuNPs, SARS CoV-2 antibody | AuNPs, SARS CoV-2 antibody | Graphene sheet, SARS CoV-2 antibody |
| Preparation & Assay reaction time (estimated) | ~50 min | >3 h | N/A |
| Assay sample-to-result time (estimated) | ~80 min (including reaction time) | >5 h | >48 h |
| Assay Results | Qualitative and Quantitative | Quantitative | Qualitative |