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. 2021 Jan 6;20:9. doi: 10.1186/s12936-020-03533-w

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Analysis of primary blood DC apoptosis in uninfected versus asymptomatically infected adults. Cells were gated on viable mononuclear cells (PBMCs), then further gated on singlets and 7-AAD negative (live) cells. Blood DCs were identified as Lin⁻ HLA-DR⁺ cells (DCs) and apoptosis determined by Annexin-V binding assays. Representative dot plots and a histogram are shown (a). Percentage of Annexin-V positive DCs in uninfected (n = 27) and asymptomatically infected (n = 8) Malian adults (b). Each circle represents one individual donor at one time point; bars represent mean with standard deviation. P-value by unpaired t-test