Table 5. . Class of immune checkpoint inhibitors and organ manifestation.
PD-1 | CTLA-4 | PD-L1 | PD-1 + CTLA-4 | |
---|---|---|---|---|
Nervous system | - | - | - | 3 |
Rheumatologic | 13 | 3 | 1 | 2 |
Skin | 24 | 6 | 2 | 3 |
Endocrine | 50 | 21 | 1 | 8 |
Lung | 17 | 1 | - | 1 |
Gastrointestinal | 10 | 5 | - | 5 |
Others | 5 | - | - | - |
Total | 119 | 36 | 4 | 22 |
CTLA-4: Cytotoxic T lymphocyte antigen-4; PD-1: Programmed cell death; PD-L1: Program death ligand.