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. 2020 Dec 23;10:606574. doi: 10.3389/fonc.2020.606574

Figure 2.

Figure 2

Diagnostic concordant case: right frontal giant-cells GBM (case n. 4). (A) Neuronavigation MR images showing the site of “A” biopsy sampling in the GBM core. (B) Intraoperative view during tumor removal with SF-guided technique. Yellowish fluorescent areas under Y560 filter activation of the surgical microscope correspond to tumor tissue (site of “A” sampling, black arrow). Both CONVIVO® ex vivo images (C) and frozen and classical histopathological sections (D) confirmed the GBM diagnosis. To note the presence of «giant cells» (red arrows), along with increased cellularity and foci of necrosis with apoptotic cells (blue arrows) in both (C, D).