Table 6.

Multivariate survival analysis for MAGED1 in TCGA-GBM dataset.

	OS			DSS			PFI
	HR	95%CI	p value	HR	95%CI	p value	HR	95%CI	p value
MAGED1 expression	1.319	0.804–2.163	0.272	1.372	0.806–2.334	0.243	0.978	0.603–1.585	0.929
Molecular Subtype
MS vs. CL (Ref.)	1.085	0.626–1.879	0.771	1.108	0.612–2.004	0.734	0.912	0.540–1.540	0.732
PN vs. CL (Ref.)	0.899	0.513–1.574	0.710	0.770	0.411–1.443	0.416	0.805	0.451–1.437	0.465
IDH status
IDH MUT vs. WT (Ref.)	0.465	0.123–1.759	0.260	0.588	0.151–2.293	0.445	0.413	0.096–1.765	0.233
MGMT promoter methylation status
Present vs. Absent (Ref.)	0.606	0.367–1.000	0.050	0.516	0.298–0.894	0.018	0.605	0.356–1.027	0.063
Age (increasing years)	1.033	1.010–1.055	0.003*	1.033	1.009–1.058	0.005*	1.010	0.988–1.032	0.345
Gender
Female vs. Male (Ref.)	0.980	0.594–1.615	0.938	1.007	0.583–1.740	0.977	1.047	0.623–1.757	0.862

OS, overall survival; DSS, disease specific survival; PFI, progression free interval; HR, hazard ratio; CI, confidence interval; CL, classical; MS, mesenchymal; PN, proneural; WT, wild type; MUT, mutant, MGMT; O-6-methylguanine-DNA methyltransferase. * indicates p < 0.05.