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STK11 mutation and drug sensitivity. (A, B) Genomics of Drug Sensitivity in Cancer (GDSC) database results showing that lung adenocarcinoma (LUAD) cells with STK11 mutations (other cancer types were excluded) are inhibited by Nutlin-3a(-) (p-value < 0.001). (C) Scatter and volcano plots showing that multiple other cancer cell types with STK11 mutations are not inhibited by Nutlin-3a(-) (p-value > 0.05).
