Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 5:M20-7866. doi: 10.7326/M20-7866

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article is made available via the PMC Open Access Subset for unrestricted re-use for research, analyses, and text and data mining through PubMed Central. Acknowledgement of the original source shall include a notice similar to the following: "© 2020 American College of Physicians. Some rights reserved. This work permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited." These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

PMC Copyright notice

Figure. Comparison of vaccine performance. The figures illustrate the performance of 4 vaccination strategies in 100 000 persons with 0.1% infected and 9000 recovered in a susceptible–exposed–infectious–recovered model: 1) no vaccination (gray line); 2) a 95%-effective, 2-dose vaccine (orange line); 3) a single-dose vaccine conferring lifetime protection (blue line); and 4) a single-dose vaccine conferring an uncertain duration of protection that is exponentially distributed with a mean of 6 mo (yellow line). The vertical axes represent the outcome of interest (cumulative infections [top] and deaths [bottom]). The horizontal axes denote the efficacy of the single-dose vaccine. The crossing point of the blue line with the orange and yellow lines denotes the efficacy levels at which the 2 single-dose vaccines match the performance of the 95%-effective, 2-dose comparator. — The figures illustrate the performance of 4 vaccination strategies in 100 000 persons with 0.1% infected and 9000 recovered in a susceptible–exposed–infectious–recovered model: 1) no vaccination (gray line); 2) a 95%-effective, 2-dose vaccine (orange line); 3) a single-dose vaccine conferring lifetime protection (blue line); and 4) a single-dose vaccine conferring an uncertain duration of protection that is exponentially distributed with a mean of 6 mo (yellow line). The vertical axes represent the outcome of interest (cumulative infections [top] and deaths [bottom]). The horizontal axes denote the efficacy of the single-dose vaccine. The crossing point of the blue line with the orange and yellow lines denotes the efficacy levels at which the 2 single-dose vaccines match the performance of the 95%-effective, 2-dose comparator.