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. 2020 Aug 7;15(6):1761–1773. doi: 10.2217/rme-2020-0023

Figure 6. . Histological analysis of microvascular density.

Figure 6. 

(A) H&E staining of the implantation site with occluded FA and scaffold. Dotted circle denotes location of scaffold. (B) Corresponding tissue section immunofluorescently stained for microvessels using α-SMA antibody. (C) Quantification of relative percent change in microvascular density in the vicinity of HGF mmRNA-releasing scaffold, compared with surrounding tissue >1000 μm in radial distance away from the scaffold (n = 3). Dotted line denotes the relative microvascular density in the surrounding tissue. Scale bar denotes 1 mm.

*Denotes statistically significant difference in comparison to surrounding tissue (p < 0.05).

FA: Femoral artery; H&E: Hematoxylin and eosin.