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(A) In the presence of the aligned collagen, a number of cells attracted to ischemic region attach to the scaffold, get transfected and produce HGF. (B) Secreted HGF attracts more cells, including local endothelial and endothelial precursor cells. (C) Endothelial cells migrated to the scaffold eventually form new capillaries along the scaffold.
EC: Endothelial cell.
