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. Author manuscript; available in PMC: 2021 Jan 6.
Published in final edited form as: Nanomedicine. 2019 Mar 1;18:31–43. doi: 10.1016/j.nano.2019.02.007

Figure 7.

Figure 7.

Cationic lipoplex loaded with siSOX2 (CL-siSOX2) inhibits expression of inflammatory markers in mice xenograft tumors. C.B.17 SCID mice with H1650 SP cells as tumor xenografts received treatment as described. (A) Immunoblotting of tumor lysates shows protein expression of (B) TLR9, (C) TLR1 and (D) IKKγ. Results were calculated as protein/β-actin ratio and presented as mean percent of the CL-siScr with SD. Statistical analysis: student t test: (treatment vs. siScr: ****P < 0.0001, treatment vs. cisplatin: ##P < 0.01; ###P < 0.001; ####P < 0.0001, and treatment vs. CL-siSOX2: ††††P < 0.0001).