Overall survival of patients treated with glasdegib. Kaplan-Meier curves of OS (A) in the entire cohort, (B) stratified by IPSS classification, and stratified by response (ie, responder/stable disease versus progressive disease/treatment failure) in (C) the overall cohort and (D) the high-risk cohort. Abbreviations: INT, intermediate; IPSS, international prognostic scoring system; PD, progressive disease; SD, stable disease; Tx, treatment.