Skip to main content
. Author manuscript; available in PMC: 2021 Feb 15.
Published in final edited form as: Int J Cancer. 2019 Jul 26;146(4):1018–1030. doi: 10.1002/ijc.32570

Figure 3.

Figure 3.

Receiver operating curve showing relationship of sensitivity and 1-specificity at various logistic regression model cut-points based on HPV 16 methylation and EPB41L3 methylation status to detect oropharyngeal cancer. Note: HPV16 methylation status was lacking for two controls. (a) All cases—ROC was calculated using 101 cases and 99 controls. (b) Early disease cases (T1–2 and N0–1, only if there is a single ipsilateral node <3 cm)—ROC was calculated using 19 cases and 99 controls. (c) Late disease cases—ROC was calculated using 82 cases and 99 controls. (d) ROC using EPB41L3 methylation alone—ROC was calculated using 101 cases and 101 controls.