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. Author manuscript; available in PMC: 2021 Feb 15.
Published in final edited form as: Int J Cancer. 2019 Jul 26;146(4):1018–1030. doi: 10.1002/ijc.32570

Table 3.

Oral gargle EPB41L3 methylation status among controls and oropharyngeal cancer cases stratified by early (T1–2 N0–1 [small tumors with only a single ipsilateral positive node <3 cm]) and late disease presentation

Methylation Controls (n = 101) All cases (n = 101) Early disease (n = 19) Late disease (n = 82) p-value1
EPB41L3
 Median 0.90 1.30 1.53 1.25 <0.0001
 Mean (SD) 0.97 (0.63) 2.59 (3.93) 2.14 (1.75) 2.69 (4.28) 0.0003
 Interquartile range (Q1-Q3) 0.73–1.13 0.97–2.87 1.00–3.07 0.93–2.87 <0.0001
1

p values are from Wilcoxon Rank Sum tests comparing across two groups, that is, control vs. case, control vs. early disease and control vs. late disease.