Table 3.
Multivariable logistic regression model for development of COVID-19 in South Korea
| Variable | Multivariable model | P-value |
|---|---|---|
| OR (95% CI) | ||
| Chronic respiratory diseases group (model1) | 1.04 (0.99, 1.09) | 0.156 |
| Chronic respiratory diseases: sensitivity analyses (model2) | ||
| COPD | 0.96 (0.85, 1.09) | 0.553 |
| Asthma | 1.01 (0.96, 1.07) | 0.464 |
| Interstitial lung disease | 1.63 (1.17, 2.26) | 0.004 |
| Lung cancer | 0.91 (0.67, 1.23) | 0.533 |
| Lung disease d/t external agent | 1.35 (0.99, 1.85) | 0.061 |
| Obstructive sleep apnea | 1.65 (1.23, 2.16) | < 0.001 |
| Tuberculosis of lung | 0.92 (0.75, 1.11) | 0.372 |
| Age, year | ||
| 20–29 | 1 | |
| 30–39 | 0.94 (0.86, 1.02) | 0.153 |
| 40–49 | 0.86 (0.80, 0.93) | < 0.001 |
| 50–59 | 0.74 (0.69, 0.79) | < 0.001 |
| 60–69 | 0.60 (0.55, 0.66) | < 0.001 |
| 70–79 | 0.47 (0.42, 0.52) | < 0.001 |
| ≥ 80 | 0.38 (0.33, 0.44) | < 0.001 |
| Income level | ||
| Q1 (Lowest) | 1 | |
| Q2 | 0.80 (0.75, 0.86) | < 0.001 |
| Q3 | 0.78 (0.73, 0.83) | < 0.001 |
| Q4 (Highest) | 0.83 (0.78, 0.88) | < 0.001 |
| Unknown | 0.75 (0.62, 0.91) | 0.004 |
| Sex, male | 1.01 (0.96, 1.06) | 0.678 |
| Residence | ||
| Seoul | 1 | |
| Gyeonggi-do | 0.90 (0.82, 0.99) | 0.038 |
| Daegu | 0.96 (0.84, 1.10) | 0.562 |
| Gyeongsangbuk-do | 0.94 (0.84, 1.05) | 0.271 |
| Other area | 0.89 (0.79, 1.00) | 0.053 |
| Underlying disability | 1.11 (1.00, 1.22) | 0.041 |
| Charlson comorbidity index (model 2) | 1.19 (1.18, 1.20) | < 0.0001 |
| Hypertension | 0.80 (0.74, 0.85) | < 0.001 |
| DM without chronic complication | 1.75 (1.63, 1.88) | < 0.001 |
| DM with chronic complication | 0.81 (0.71, 0.92) | 0.001 |
| Peripheral vascular disease | 0.75 (0.67, 0.83) | < 0.001 |
| Renal disease | 0.91 (0.75, 1.11) | 0.371 |
| Rheumatic disease | 0.98 (0.85, 1.12) | 0.734 |
| Dementia | 1.96 (1.72, 2.22) | < 0.001 |
| Peptic ulcer disease | 1.48 (1.37, 1.59) | < 0.001 |
| Hemiplegia or paraplegia | 2.69 (2.11, 3.44) | < 0.001 |
| Moderate or severe liver disease | 0.59 (0.33, 1.06) | 0.076 |
| Mild liver disease | 2.12 (1.99, 2.27) | < 0.001 |
| Cerebrovascular disease | 0.99 (0.88, 1.11) | 0.886 |
| Congestive heart failure | 2.88 (2.60, 3.19) | < 0.001 |
| Myocardial infarction | 4.55 (3.95, 5.24) | < 0.001 |
| Malignancy | 2.04 (1.93, 2.15) | < 0.001 |
| Metastatic solid tumor | 0.95 (0.84, 1.07) | 0.387 |
| AIDS/HIV | 4.21 (1.84, 9.64) | < 0.001 |
AUC of the multivariable models: 0.81 (95% CI 0.80 to 0.81)
OR, odds ratio; CI, confidence interval; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; AIDS, acquired immune deficiency syndrome; HIV, Human Immunodeficiency Virus