Table 4.
Multivariable logistic regression model for hospital mortality in COVID-19 patients (n = 7780, death = 251, 3.2%)
| Variable | Multivariable model | P-value |
|---|---|---|
| OR (95% CI) | ||
| Chronic respiratory diseases (model 1) | 1.19 (0.86, 1.64) | 0.299 |
| Chronic respiratory diseases: sensitivity analyses (model 2) | ||
| COPD | 1.56 (1.06, 2.2) | 0.024 |
| Asthma | 1.03 (0.76, 1.41) | 0.834 |
| Interstitial lung disease | 1.83 (0.74, 4.55) | 0.193 |
| Lung cancer | 1.82 (0.80, 4.14) | 0.154 |
| Lung disease d/t external agent | 3.54 (1.70, 7.38) | < 0.001 |
| Obstructive sleep apnea | 0.47 (0.06, 3.94) | 0.486 |
| Tuberculosis of lung | 1.65 (0.48, 5.64) | 0.423 |
| Age, 10 year increase | 2.85 (2.40, 3.38) | < 0.001 |
| Income level | ||
| Q1 (Lowest) | 1 | |
| Q2 | 0.96 (0.59, 1.57) | 0.882 |
| Q3 | 1.08 (0.70, 1.65) | 0.739 |
| Q4 (Highest) | 0.89 (0.652, 1.30) | 0.554 |
| Unknown | 0.67 (0.18, 2.54) | 0.560 |
| Sex, male | 2.12 (1.55, 2.88) | < 0.001 |
| Residence | ||
| Seoul | 1 | |
| Gyeonggi-do | 2.26 (0.75, 6.86) | 0.148 |
| Daegu | 2.60 (0.74, 9.16) | 0.136 |
| Gyeongsangbuk-do | 2.40 (0.77, 7.49) | 0.133 |
| Other area | 1.69 (0.50, 5.72) | 0.401 |
| Underlying disability | 1.33 (0.94, 1.89) | 0.109 |
| Charlson comorbidity index, model 2 | 1.80 (1.32, 2.44) | < 0.001 |
| Hypertension | 1.36 (0.89, 2.06) | 0.153 |
| DM without chronic complication | 1.87 (1.35, 2.59) | < 0.001 |
| DM with chronic complication | 1.61 (1.06, 2.45) | 0.027 |
| Peripheral vascular disease | 1.19 (0.81, 1.76) | 0.76 |
| Renal disease | 1.47 (0.87, 2.47) | 0.148 |
| Rheumatic disease | 0.58 (0.30, 1.12) | 0.107 |
| Dementia | 1.61 (1.11, 2.32) | 0.011 |
| Peptic ulcer disease | 1.04 (0.73, 1.49) | 0.818 |
| Hemiplegia or paraplegia | 1.92 (1.03, 3.59) | 0.040 |
| Moderate or severe liver disease | 5.12 (1.32, 19.90) | 0.018 |
| Mild liver disease | 0.80 (0.58, 1.10) | 0.170 |
| Cerebrovascular disease | 0.57 (0.38, 0.87) | 0.009 |
| Congestive heart failure | 1.91 (1.38, 2.66) | < 0.001 |
| Myocardial infarction | 0.79 (0.47, 1.33) | 0.374 |
| Malignancy | 1.07 (0.78, 1.46) | 0.694 |
| Metastatic solid tumor | 1.37 (0.85, 2.19) | 0.192 |
| AIDS/HIV | 1.43 (0.11, 19.37) | 0.788 |
AUC of the multivariable models: 0.83 (95% CI 0.82 to 0.83)
OR, odds ratio; CI, confidence interval; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; AIDS, acquired immune deficiency syndrome; HIV, Human Immunodeficiency Virus