Fig 6. Inhibition of CXCL10 or IFNγ impairs CD20-TCB-dependent T cell infiltration.

a) Subcutaneous WSU DLCL2-derived tumors between 200 and 800 mm³ were intravenously treated with 0.5 mg/kg CD20-TCB in the presence of αCXCL10 or αIFNγ antibodies (10 mg/kg), or with suitable vehicle, once per week. n = 9. Shown are mean values +/- s.d. for tumor volume over time. Unpaired t-test, *p<0.05. b) Representative histology of tumors at termination. Blue: Nuclear counterstain, brown: CD3. c) Quantification of infiltration at termination (CD3⁺ T cells per tumor area). Statistics: One-way Anova, **p< 0.01, ***p<0.005. d) Correlation between infiltration and tumor growth.