Skip to main content
. 2021 Jan 6;7(2):eabd5230. doi: 10.1126/sciadv.abd5230

Fig. 1. Major models of AmB’s mechanism of action in a lipid membrane.

Fig. 1

(A and B) Chemical structures of AmB (A) and ergosterol (B), respectively. (C) Classic ion channel model. (D) Sterol sponge model where large extramembranous aggregates sequester ergosterol from lipid bilayers.