Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 13;26(8):703–715. doi: 10.1177/1753425920961157

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 4. — Correlation analysis between the ratios of IL-10/IL-12 mRNA and TGF-β/TNF-α mRNA in MDSCs and clinical parameters in MDS patients. (a) Percentage of blast cells in bone marrow was positively correlated with the ratio of IL-10/IL-12 mRNA and TGF-β/TNF-α mRNA in MDSCs of MDS patients. (b) Dot diagrams present the ratio of IL-10/IL-12 mRNA relative expression in patients with bone marrow blasts < 5% and blasts ≥ 5% MDS. (c) Correlation analysis between the ratio of TGF-β/TNF-α mRNA in MDSCs and peripheral blood T lymphocyte subsets (CD3⁺CD8⁺ cells %; CD3⁺CD4⁺ cells %; CD4⁺/CD8⁺ ratio) of MDS patients. (d) Ratio of IL-10/IL-12 mRNA relative expression in patients with an absolute neutrophil count (ANC) < 0.8 × 10⁹/l and patients with an ANC of ≥ 0.8 × 10⁹/l. *P < 0.05.