Table 2:
Preliminary Objective Effectiveness Measures
| Baseline (N=9) | Week 12 (N=9) | Difference (N=9) | Percent Change | p value | |
|---|---|---|---|---|---|
| Anthropometric | |||||
| Weight, kg | 93.7±9.7 | 89.4±12.1 | −4.3±3.2 | −4.9±3.7 | <0.001 |
| BMI, kg/m2 | 35.4±3.4 | 33.6±3.7 | −1.7±1.2 | −4.9±3.7 | 0.002 |
| Waist circumference, cm | 116.3±7.5 | 108.7±9.2 | −7.6±4.9 | −6.5±4.4 | 0.002 |
| Hip circumference, cm | 121.0±5.3 | 116.9±7.3 | −4.1±4.0 | −3.4±3.4 | 0.02 |
| Waist to hip ratio | 0.96±0.05 | 0.93±0.03 | −0.03±0.04 | −3.2±4.1 | 0.04 |
| Objective Measures | |||||
| 6 min walk test, m | 400.6±81.0 | 448.1±122.0 | 47.5±83.0 | 11.5±18.93 | 0.12 |
| Max Gait Speed, s | 1.16±0.21 | 1.35±0.23 | 0.19±0.15 | 17.7±13.3 | 0.004 |
| Mean Grip Strength, kg | 29.1±7.5 | 35.2±6.7 | 6.2±5.1 | --- | 0.02 |
| 5-Times Sit To Stand, s | 12.5±4.0 | 9.6±5.2 | −2.9±2.9 | --- | 0.02 |
| Subjective Measures | |||||
| Late-Life Functionality | |||||
| Total | 58.9±11.5 | 62.6±11.1 | 3.7±4.8 | 6.9±7.3 | 0.05 |
| Upper extremity | 77.1±15.4 | 83.9±15.9 | 6.8±12.0 | 10.0±14.2 | 0.13 |
| Basic lower extremity | 71.3±16.5 | 80.8±17.3 | 9.5±12.4 | 14.5±14.6 | 0.05 |
| Patient Activation Measure | 68.1±17.5 | 77.3±19.3 | 9.22±11.3 | 15.0±15.6 | 0.04 |
| PROMIS, total | |||||
| Mental Health T score | 52.0±3.8 | 55.7±5.9 | 3.60±3.5 | 6.8±6.5 | 0.02 |
| Physical Health T score | 46.6±6.5 | 48.6±6.8 | 2.95±4.4 | 6.9±11.2 | 0.10 |
All values listed are mean (SD), or count (%)
Abbreviations: BMI: body mass index; PROMIS – patient reported outcomes measurement information systems.