Table 1.
Demographic, clinical, and laboratory features of patients diagnosed as luminal A with bone metastasis.
| Variable | Training set (n = 2,223) | Validating set (n = 948) | P value |
|---|---|---|---|
| Follow time (mo) | |||
| Mean | 30.4 | 29.8 | |
| Range | 2-83 | 2-83 | |
| Number of events | |||
| Live | 1059 (47.6%) | 462 (48.7%) | |
| Dead | 1164 (52.4%) | 486 (51.3%) | |
| Age (y) | 0.387 | ||
| <55 | 776 (34.9%) | 307 (32.4%) | |
| 55-78 | 1220 (54.9%) | 539 (56.9%) | |
| >78 | 227 (10.2%) | 102 (10.8%) | |
| Race | 0.748 | ||
| White | 1743 (78.4%) | 742 (78.3%) | |
| Black | 300 (13.5%) | 135 (14.2%) | |
| Other | 180 (8.1%) | 71 (7.5%) | |
| Grade | 0.340 | ||
| I | 292 (13.1%) | 121 (12.8%) | |
| II | 1190 (53.5%) | 520 (54.9%) | |
| III | 734 (33.0%) | 307 (32.4%) | |
| IV | 7 (0.3%) | 0 | |
| Laterality | 0.260 | ||
| Left | 1138 (51.2%) | 474 (50.0%) | |
| Right | 1085 (48.8%) | 473 (49.9%) | |
| Bilateral | 0 | 1 (0.01%) | |
| Histological type | 0.731 | ||
| IDC | 1607 (72.3%) | 678 (71.5%) | |
| IDC + ILC | 136 (6.1%) | 65 (6.9%) | |
| Other | 480 (21.6%) | 205 (21.6%) | |
| T stage | 0.806 | ||
| T1-2 | 1183 (53.2%) | 509 (53.7%) | |
| T3-4 | 1040 (46.8%) | 439 (46.3%) | |
| N stage | 0.867 | ||
| N0 | 522 (23.5%) | 220 (23.2%) | |
| N1-3 | 1701 (76.5%) | 728 (76.8%) | |
| Size (mm) | 0.083 | ||
| <36 | 973 (43.8%) | 454 (47.9%) | |
| 36-85 | 1019 (45.8%) | 396 (41.8%) | |
| >85 | 231 (10.4%) | 98 (10.3%) | |
| Primary site | 0.134 | ||
| Breast, NOS | 487 (21.9%) | 252 (26.6%) | |
| Central portion of breast | 180 (8.1%) | 66 (7.0%) | |
| Lower-inner quadrant of breast | 94 (4.2%) | 41 (4.3%) | |
| Lower-outer quadrant of breast | 140 (6.3%) | 55 (5.8%) | |
| Upper-inner quadrant of breast | 179 (8.1%) | 64 (6.8%) | |
| Upper-outer quadrant of breast | 619 (27.8%) | 248 (26.2%) | |
| Other | 524 (23.6%) | 222 (23.4%) | |
| Surgery | 0.734 | ||
| Yes | 849 (38.2%) | 356 (37.6%) | |
| No | 1374 (61.8%) | 592 (62.4%) | |
| Radiation | <0.0001 | ||
| Yes | 962 (43.3%) | 516 (54.4%) | |
| No | 1261 (56.7%) | 432 (45.6%) | |
| Chemotherapy | 0.322 | ||
| Yes | 1058 (47.6%) | 433 (45.7%) | |
| No | 1165 (52.4%) | 515 (54.3%) | |
| Brain | 0.009 | ||
| Yes | 103 (4.6%) | 25 (2.6%) | |
| No | 2120 (95.4%) | 923 (97.4%) | |
| Liver | 0.026 | ||
| Yes | 347 (15.6%) | 119 (12.6%) | |
| No | 1876 (84.4%) | 829 (87.4%) | |
| Lung | 0.947 | ||
| Yes | 469 (21.1%) | 199 (21.0%) | |
| No | 1754 (78.9%) | 749 (79.0%) | |
| ER | 0.097 | ||
| Positive | 2208 (99.3%) | 936 (98.7%) | |
| Negative | 15 (0.7%) | 12 (1.3%) | |
| PR | 0.973 | ||
| Positive | 1903 (85.6%) | 813 (85.8%) | |
| Negative | 317 (14.3%) | 134 (14.1%) | |
| Borderline | 3 (0.1%) | 1 (0.1%) | |
| Insurance | 0.007 | ||
| Yes | 2127 (95.7%) | 926 (97.7%) | |
| No | 96 (4.3%) | 22 (2.3%) | |
| Marital status | 0.004 | ||
| Yes | 1127 (50.7%) | 428 (45.1%) | |
| No | 1096 (49.3%) | 520 (54.9%) |