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Huaier extract downregulates the CHOP and GRP78 protein expression in vivo. (a) Western blot analysis of the expression of GRP78 and CHOP in kidney sections 28 days after ischemia-reperfusion injury (IRI). (b) Immunohistochemical analysis of the expression of GRP78 and CHOP 28 days after IRI. Scale bar : 100 μm. (c) The mRNA expression of GRP78 and CHOP by real-time PCR. ∗∗P < 0.01 (∗vs. the sham group); #P < 0.05; ##P < 0.01 (vs. the IRI group).
