Figure 3.
Huaier extract downregulates CHOP and GRP78 and upregulates miR-1271 in an endoplasmic reticulum stress model in HK-2 human kidney epithelial cells. (a) Western blot analysis of the expression of GRP78 and CHOP in kidney sections. (b) The mRNA expression of GRP78 and CHOP by real-time PCR. (c) The relative expression of miR-1271 by real-time PCR. ∗∗P < 0.01, (∗vs. the sham group),#P < 0.05, ##P < 0.01 (vs. the ischemia-reperfusion injury group). ∗P < 0.05 (vs. the control group), ∗∗P < 0.01, ##P < 0.01 (vs. the thapsigargin-treated group).