Table 1.
Clinical and laboratory data of the 75 patients.
| Values | |
|---|---|
| Variants (N (%)) | |
| MPA | 38 (50.7%) |
| GPA | 21 (28.0%) |
| EGPA | 16 (21.3%) |
| Demographic data | |
| Age (years) | 58.9 ± 15.1 |
| Male gender (N (%)) | 26 (34.7%) |
| Disease duration (months) | 18.2 ± 32.2 |
| AAV-specific indices | |
| BVAS | 9.6 ± 6.8 |
| FFS (2009) | 1.3 ± 0.9 |
| VDI | 3.2 ± 1.7 |
| SF-36 PCS score | 49.9 ± 23.3 |
| SF-36 MCS score | 56.8 ± 21.5 |
| Clinical manifestations (N (%)) | |
| General | 26 (34.7%) |
| Cutaneous | 9 (12.0%) |
| Mucous membrane and eye | 5 (6.7%) |
| Ear, nose, and throat | 35 (46.7%) |
| Pulmonary | 48 (64.0%) |
| Cardiovascular | 5 (6.7%) |
| Abdominal | 0 (0.0%) |
| Renal | 38 (50.7%) |
| Nervous system | 16 (21.3%) |
| ANCA positivity (N (%)) | |
| P-ANCA | 41 (54.7%) |
| C-ANCA | 7 (9.3%) |
| MPO-ANCA | 37 (49.3%) |
| PR3-ANCA | 6 (8.0%) |
| ANCA positivity | 49 (65.3%) |
| Laboratory data | |
| WBC count (/mm3) | 8.9 ± 4.4 |
| Hemoglobin (g/dL) | 11.6 ± 2.4 |
| Platelet count (×1000/mm3) | 303.3 ± 141.6 |
| Blood urea nitrogen (mg/dL) | 24.8 ± 16.7 |
| Creatinine (mg/dL) | 1.7 ± 1.8 |
| Total protein (g/dL) | 6.3 ± 0.7 |
| Serum albumin (g/dL) | 3.6 ± 0.7 |
| AST (IU/L) | 20.9 ± 12.8 |
| ALT (IU/L) | 24.4 ± 20.9 |
| ESR (mm/hr) | 44.6 ± 33.3 |
| CRP (mg/L) | 19.4 ± 39.8 |
| SAA (ng/mL) | 876.0 ± 825.0 |
Values are expressed as mean ± standard deviation or number (percentage). MPA: microscopic polyangiitis; GPA: granulomatosis with polyangiitis; EGPA: eosinophilic granulomatosis with polyangiitis; AAV: ANCA-associated vasculitis; ANCA: antineutrophil cytoplasmic antibody; BVAS: Birmingham Vasculitis Activity Score; FFS: five-factor score; VDI: vasculitis damage index; SF-36: Short-Form 36-Item Health Survey; PCS: physical component summary; MCS: mental component summary; P: perinuclear; C: cytoplasmic; MPO: myeloperoxidase; PR3: proteinase 3; WBC: white blood cell; AST: aspartate aminotransferase; ALT: alanine aminotransferase; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; SAA: serum amyloid A.