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Schematic showing how seawater (SW) and adipose-derived stem cells (ADSCs) regulate wound healing through the EGFR/MEK/ERK signaling pathway (a). The EGF protein expression levels were significantly higher in the control and SW+ADSC groups than in the SW and SW+DMEM groups (b). Hematoxylin and eosin (H&E) staining for wound repair, skin thickness, and a number of subcutaneous appendages (c). The red arrow denotes a hair follicle. Adapted from a previous study [165], with permission.
