Table 3.
Clinical data from the neurological evaluation
| Mild | Moderate | Severe | Encephalopathy cases | Cases without encephalopathy | |
|---|---|---|---|---|---|
| Total | 12 | 18 | 13 | 43 | 12 |
| Clinical data at neurology consultation | |||||
| Heart rate > 100 bpm | 3 (25%) | 9 (50%) | 4 (31%) | 16 (37%) | 2 (17%) |
| Mean blood pressure < 70 mmHg | 0 (0%) | 1 (6%) | 0 (0%) | 1 (2%) | 0 (0%) |
| Oxygen saturation < 90% | 0 (0%) | 1 (6%) | 1 (8%) | 2 (5%) | 0 (0%) |
| Receiving supplemental O2 | 6 (50%) | 14 (78%) | 10 (77%) | 30 (70%) | 6 (50%) |
| Glasgow coma scale (mean) | 14.0 (14.0–14.5) | 13.0 (8.5–14.0) | 11.0 (6.0–13.0) | 14.0 (9.5–14.0) | 15.0 (15.0–15.0) |
| Richmond agitation–sedation scale (mean) | 0 (0–0) | − 0.5 (− 3.3 to 0) | − 5.0 (− 5.0 to − 4.3) | − 1.0 (− 5.0 to 0) | 0 (0–0) |
| Neurological exam | |||||
| Behavioral changes | 4 (33%) | 0 (0%) | 0 (0%) | 4 (9%) | 0 (0%) |
| Psychomotor agitation | 0 (0%) | 0 (0%) | 1 (8%) | 1 (2%) | 0 (0%) |
| Oriented to time and space | 6 (46%) | 0 (0%) | 0 (0%) | 6 (14%) | 12 (100%) |
| Nuchal rigidity | 0/9 (0%) | 0/13 (0%) | 0/3 (0%) | 0/25 (0%) | 0/8 (0%) |
| Quadriparesis | 2 (17%) | 2 (11%) | 1 (8%) | 5 (12%) | 1 (8%) |
| Increased deep tendon reflexes | 1 (8%) | 1 (6%) | 0 (0%) | 2 (5%) | 0 (0%) |
| Myoclonus | 2 (17%) | 2 (11%) | 2 (15%) | 6 (14%) | 0 (0%) |
| Other neurological diagnoses | |||||
| Acute neurovascular disease | 0 (0%) | 3 (17%) | 1 (8%) | 4 (9%) | 1 (8%) |
| Seizures in patients without prior epilepsy | 0 (0%) | 0 (0%) | 3 (23%) | 3 (7%) | 0 (0%) |
| Seizures in patients with prior epilepsy | 2 (17%) | 0 (0%) | 0 (0%) | 2 (5%) | 3 (25%) |
Data are median (IQR), mean (SD) or n/N (%). N is the total number of patients with available data and n the number of patients presenting the finding