3D T1-weighted images and thalamus segmentations of manual tracing, FreeSurfer, FSL-FIRST, CAT12, GIF and VolBrain. Segmentations of the thalamus bilaterally in the axial plane of two MS patients, revealing the inferior portion of the thalamus of one cognitively impaired patient (top row) and the middle part of the thalamus of one cognitively preserved patient (bottom row) for: manual tracings (A), FreeSurfer (B), FSL-FIRST (C), CAT12 (D), GIF (E) and VolBrain (F) segmentations.