Table 8.
Summary of results of the general linear regression analysis with CII as the dependent variable, for each vendora.
Thalamus volumesb | GE (N = 18) |
Philips (N = 18) |
Siemens (N = 21) |
|||
---|---|---|---|---|---|---|
B (95%CI) | p-Value | B (95%CI) | p-Value | B (95%CI) | p-Value | |
Manual outlines | ||||||
Left thalamus | 0.32 (-1.06 – 1.70) | 0.63 | −0.47 (-1.50 – 0.57) | 0.36 | −1.32 (-2.02 – (-0.62)) | 0.001 |
Right thalamus | 0.08 (-1.28 – 1.44) | 0.90 | −0.58 (-1.77 – 0.61) | 0.32 | −1.15 (-1.85 – (-0.44)) | 0.003 |
FreeSurfer | ||||||
Left thalamus | −0.48 (-1.88 – 0.92) | 0.48 | −1.79 (-3.64 – 0.05) | 0.06 | −1.48 (-2.46 – (-0.51)) | 0.005 |
Right thalamus | −0.57 (-2.09 – 0.95) | 0.44 | −1.65 (-3.26 – (-0.04)) | 0.045 | −1.68 (-2.79 – (-0.56)) | 0.005 |
FSL-FIRST | ||||||
Left thalamus | −0.05 (-1.40 – 1.30) | 0.94 | −2.11 (-4.14 – (-0.08)) | 0.043 | −1.40 (-2.41 – (-0.39)) | 0.009 |
Right thalamus | −0.12 (-1.50 – 1.26) | 0.86 | −1.56 (-3.87 – 0.74) | 0.17 | −1.34 (-2.45 – (-0.24)) | 0.020 |
CAT12 | ||||||
Left thalamus | −0.27 (-1.20 – 0.67) | 0.56 | −2.00 (-3.38 – (-0.62)) | 0.007 | −1.38 (-2.17 – (-0.60)) | 0.001 |
Right thalamus | −0.34 (-1.33 – 0.66) | 0.49 | −1.51 (-2.94 – (-0.09)) | 0.038 | −1.53 (-2.33 – (-0.73)) | 0.001 |
GIF | ||||||
Left thalamus | −0.82 (-2.80 – 1.15) | 0.39 | -0.253 (-6.69 – 1.62) | 0.22 | −1.62 (-3.08 – (-0.17)) | 0.031 |
Right thalamus | −0.90 (-2.87 – 1.07) | 0.35 | −1.48 (-4.91 – 1.94) | 0.37 | −1.71 (-3.22 – (-0.19)) | 0.029 |
VolBrain | ||||||
Left thalamus | −0.22 (-1.54 – 1.10) | 0.73 | −1.83 (-3.78 – 1.20) | 0.06 | −1.53 (-2.40 – (-0.65)) | 0.002 |
Right thalamus | −0.24 (-1.75 – 1.28) | 0.75 | −1.59 (-3.31 – 0.13) | 0.07 | −1.65 (-2.57 – (-0.72)) | 0.001 |
Contrast-to-noise ratio | GE (N = 18) | Philips (N = 18) | Siemens (N = 21) | |||
Left thalamus | 2.11 ± 0.66 | 1.74 ± 0.48 | 1.04 ± 0.35 | |||
Right thalamus | 2.11 ± 0.64 | 1.78 ± 0.47 | 1.18 ± 0.37 |
Abbreviations: B = unstandardized regression coefficient; CI = confidence interval; CII = Cognitive Impairment Index.aAll regression analysis were corrected for center and age; b Thalamus volumes were multiplied by the head-normalization factor derived from SIENAX; p-values in bold represent significant values.