Table 2.
Clinical chemistry values after treatment with Phytase TSP concentrate for 90 days.
| Parameter (units) | Sex | After the 90-day main study |
|||
|---|---|---|---|---|---|
| Control 0 mg/kg bw/d |
Low-dose 100 mg/kg bw/d |
Mid-dose 500 mg/kg bw/d |
High-dose 1000 mg/kg bw/d |
||
| Glucose (mmol/l) | M | 6.908 ± 0.436 | 7.135 ± 0.499 | 7.234 ± 0.981 | 7.028 ± 0.781 |
| F | 6.794 ± 0.712 | 6.592 ± 0.353 | 6.246 ± 0.515 | 6.642 ± 0.958 | |
| Sodium (mmol/l) | M | 144.5 ± 1.8 | 144.9 ± 1.4 | 143.7 ± 2.7 | 144.1 ± 1.4 |
| F | 144.2 ± 1.6 | 143.7 ± 1.5 | 143.0 ± 2.1 | 142.5 ± 1.3* | |
| Potassium (mmol/l) | M | 4.34 ± 0.22 | 4.38 ± 0.37 | 4.13 ± 0.33 | 4.29 ± 0.28 |
| F | 3.74 ± 0.35 | 3.86 ± 0.13 | 3.86 ± 0.33 | 3.79 ± 0.28 | |
| Chloride (mmol/l) | M | 104.1 ± 1.4 | 104.3 ± 1.9 | 102.8 ± 2.1 | 103.7 ± 1.6 |
| F | 104.0 ± 1.8 | 104.4 ± 1.8 | 103.9 ± 2.1 | 103.1 ± 1.5 | |
| Calcium (mmol/l) | M | 2.548 ± 0.068 | 2.634 ± 0.074 | 2.529 ± 0.111 | 2.531 ± 0.098 |
| F | 2.619 ± 0.082 | 2.616 ± 0.053 | 2.575 ± 0.100 | 2.545 ± 0.104 | |
| Phosphorous (mmol/l) | M | 2.261 ± 0.173 | 2.268 ± 0.117 | 2.236 ± 0.202 | 2.256 ± 0.165 |
| F | 1.859 ± 0.406 | 1.979 ± 0.196 | 1.942 ± 0.202 | 1.908 ± 0.224 | |
| Urea (mmol/l) | M | 7.53 ± 0.85 | 7.36 ± 1.35 | 7.08 ± 1.07 | 6.90 ± 1.07 |
| F | 8.11 ± 1.43 | 7.13 ± 0.91 | 7.53 ± 1.02 | 8.43 ± 1.50 | |
| Creatinine (μmol/l) | M | 29.9 ± 4.5 | 27.6 ± 2.5 | 30.4 ± 5.4 | 29.3 ± 4.1 |
| F | 42.7 ± 5.9 | 38.6 ± 6.7 | 37.9 ± 4.1 | 37.7 ± 5.8 | |
| Bilirubin (μmol/l) | M | 2.2 ± 1.0 | 2.2 ± 0.9 | 0.8 ± 1.3* | 1.5 ± 1.4 |
| F | 2.6 ± 0.9 | 1.9 ± 1.1 | 2.1 ± 1.2 | 1.4 ± 1.4* | |
| Bile acids (μmol/l) | M | 40.6 ± 20.7 | 42.2 ± 23.4 | 38.6 ± 27.2 | 32.5 ± 21.0 |
| F | 71.3 ± 37.4 | 34.6 ± 17.4 | 64.8 ± 38.4 | 83.1 ± 91.5 | |
| LDH (μkat/l) | M | 6.442 ± 3.287 | 4.957 ± 3.123 | 4.490 ± 3.539 | 6.708 ± 4.028 |
| F | 5.856 ± 1.396 | 6.438 ± 2.032 | 9.167 ± 4.909* | 5.963 ± 2.111 | |
| ALT (μkat/l) | M | 0.807 ± 0.216 | 0.862 ± 0.140 | 0.874 ± 0.167 | 0.891 ± 0.155 |
| F | 0.753 ± 0.200 | 0.674 ± 0.107 | 0.844 ± 0.620 | 0.797 ± 0.217 | |
| AST (μkat/l) | M | 1.420 ± 0.277 | 1.467 ± 0.268 | 1.593 ± 0.281 | 1.597 ± 0.175 |
| F | 1.441 ± 0.293 | 1.363 ± 0.160 | 1.846 ± 1.095 | 1.488 ± 0.289 | |
| GGT (μkat/l) | M | 0.155 ± 0.015 | 0.163 ± 0.013 | 0.149 ± 0.021 | 0.151 ± 0.013 |
| F | 0.152 ± 0.013 | 0.153 ± 0.015 | 0.174 ± 0.045 | 0.163 ± 0.018 | |
| ALP (μkat/l) | M | 1.621 ± 0.278 | 1.621 ± 0.379 | 1.970 ± 0.420 | 1.986 ± 0.556 |
| F | 1.095 ± 0.386 | 0.729 ± 0.127* | 0.811 ± 0.201* | 1.008 ± 0.143 | |
| Cholesterol (mmol/l) | M | 2.259 ± 0.425 | 1.810 ± 0.184* | 1.751 ± 0.291* | 1.856 ± 0.350* |
| F | 2.203 ± 0.737 | 2.282 ± 0.369 | 2.281 ± 0.466 | 2.088 ± 0.349 | |
| Triglycerides (mmol/l) | M | 0.877 ± 0.249 | 0.721 ± 0.22 | 0.948 ± 0.286 | 0.884 ± 0.267 |
| F | 1.115 ± 0.581 | 0.862 ± 0.218 | 0.955 ± 0.420 | 1.026 ± 0.568 | |
| Total protein (g/l) | M | 66.7 ± 3.7 | 64.2 ± 3.0 | 62.5 ± 3.5* | 63.7 ± 3.3 |
| F | 72.3 ± 2.2 | 69.1 ± 3.4* | 68.6 ± 3.7* | 68.4 ± 3.2* | |
| Albumin (g/l) | M | 13.2 ± 1.0 | 13.8 ± 0.6 | 11.4 ± 2.4* | 12.3 ± 0.9 |
| F | 15.1 ± 1.2 | 15.7 ± 1.2 | 14.9 ± 1.2 | 14.7 ± 1.0 | |
| Globulin (g/l) | M | 53.5 ± 3.4 | 50.4 ± 2.5* | 51.1 ± 2.8 | 51.5 ± 3.2 |
| F | 57.2 ± 2.1 | 53.4 ± 2.5* | 53.7 ± 3.2* | 53.7 ± 3.0* | |
| Albumin/Globulin | M | 0.247 ± 0.021 | 0.274 ± 0.010 | 0.224 ± 0.048 | 0.239 ± 0.022 |
| F | 0.265 ± 0.025 | 0.294 ± 0.014* | 0.278 ± 0.024 | 0.274 ± 0.023 | |
LDH, lactate dehydrogenase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma glutamyl transpeptidase; ALP, alkaline phosphatase. Values are mean ± SD (n = 15 per group in the control and high-dose groups, n = 10 in the low- and mid-dose groups.
*
Indicates statistically significant difference from control diet p<0.05.