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. 2020 Dec 31;8:139–147. doi: 10.1016/j.toxrep.2020.12.015

Table 3.

Organ weights of male rats following treatment with Phytase TSP concentrate for 90 days.

Parameter (units) Control
0 mg/kg bw/d
Low-dose
100 mg/kg bw/d
Mid-dose
500 mg/kg bw/d
High-dose
1000 mg/kg bw/d
Absolute organ weight (g)
Body weight 487.10 ± 24.15 501.80 ± 30.44 492.00 ± 16.87 497.20 ± 39.35
Liver 15.029 ± 1.372 15.615 ± 1.392 15.461 ± 1.877 15.983 ± 1.567
Kidneys 3.721 ± 0.358 3.753 ± 0.314 3.544 ± 0.335 3.681 ± 0.217
Spleen 0.812 ± 0.098 0.866 ± 0.118 0.819 ± 0.132 0.874 ± 0.107
Brain 2.039 ± 0.074 2.029 ± 0.082 2.059 ± 0.153 2.084 ± 0.107
Heart 1.341 ± 0.148 1.406 ± 0.117 1.375 ± 0.151 1.395 ± 0.162
Thymus 0.326 ± 0.080 0.284 ± 0.048 0.320 ± 0.063 0.303 ± 0.047
Adrenals 0.0781 ± 0.0132 0.0885 ± 0.0124 0.1010 ± 0.0187* 0.0881 ± 0.0239
Thyroid gland 0.0360 ± 0.0073 0.0429 ± 0.006 0.0390 ± 0.0071 0.0401 ± 0.0097
Testes 4.011 ± 0.315 4.376 ± 0.197* 4.071 ± 0.273 4.217 ± 0.459
Prostate 1.1245 ± 0.2517 1.0828 ± 0.2559 1.1305 ± 0.3797 0.8142 ± 0.2029*
Epididymides 1.648 ± 0.122 1.719 ± 0.089 1.680 ± 0.099 1.593 ± 0.121



Relative organ to body weight ratio
Liver 30.930 ± 3.370 31.128 ± 2.260 31.379 ± 3.234 32.167 ± 2.185
Kidneys 7.660 ± 0.876 7.476 ± 0.346 7.196 ± 0.534 7.420 ± 0.358
Spleen 1.668 ± 0.205 1.722 ± 0.162 1.662 ± 0.245 1.755 ± 0.118
Brain 4.196 ± 0.269 4.053 ± 0.221 4.193 ± 0.390 4.215 ± 0.407
Heart 2.756 ± 0.303 2.809 ± 0.278 2.794 ± 0.300 2.819 ± 0.368
Thymus 0.671 ± 0.169 0.564 ± 0.075 0.651 ± 0.118 0.612 ± 0.095
Adrenals 0.1606 ± 0.0279 0.1767 ± 0.0255 0.2046 ± 0.0336* 0.1771 ± 0.0441
Thyroid gland 0.0742 ± 0.0158 0.0856 ± 0.0124 0.0792 ± 0.0141 0.0812 ± 0.0215
Testes 8.252 ± 0.784 8.739 ± 0.477 8.282 ± 0.601 8.512 ± 0.996
Prostate 2.3048 ± 0.4891 2.1733 ± 0.5643 2.2915 ± 0.7360 1.6367 ± 0.4078*
Epididymides 3.393 ± 0.339 3.435 ± 0.233 3.417 ± 0.233 3.215 ± 0.284