Table 2.
The effects of synthetic tryptanthrin agent on acute inflammation and pulmonary oedema induced inflammatory responses in mice.
| Compound | Doses (mg/kg) | Acute Inflammation | % Inhibition (AI) | Pulmonary Oedema | % inhibition (PO) |
|---|---|---|---|---|---|
| Negative control (DMSO) | 0.3 mL | 0.109 ± 0.006 | 0 | 83.3 ± 2.2 | 0 |
| Tryptanthrin | 6 12 24 |
0.048 ± 0.011∗ 0.036 ± 0.022∗ 0.022 ± 0.007∗ |
55.963 66.972 79.816 |
61.98 ± 10.78 56.38 ± 9.32 54.77 ± 11.59∗ |
25.59 32.31 34.25 |
| Indomethacin | 10 | 0.038 ± 0.005∗ | 65.137 | 60.0 ± 1.1 | 27.97 |
Values represent means ± SEM of 5 animals ∗p < 0.05.