Table 2.

Relation between clinicopathological features and expression of miR-301 and PTEN in ESCC patients

Clinicopathological feature	N	Expression of miR-301		P value	PTEN mRNA expression		P value
		High expression (n = 55)	Low expression (n = 55)		High expression (n = 55)	Low expression (n = 55)
Age (years)
> 60	84	44	40	0.501	41	43	0.823
≤ 60	26	11	15		14	12
Gender
Male	78	37	41	0.529	36	42	0.294
Female	32	18	14		19	13
TNM stage
I + II	60	20	40	< 0.001	38	22	0.004
III	50	35	15		17	33
LNM
No	71	27	44	0.001	38	23	0.007
Yes	39	28	11		17	32
Tumor size (cm)
≥ 5	65	35	30	0.438	29	36	0.244
< 5	45	20	25		26	19
Tumor differentiation
Moderate and high differentiation	78	35	43	0.141	44	34	0.058
Poor differentiation	32	20	12		11	21
Tumor location
Upper	13	8	5	0.556	5	8	0.556
Mid-lower	97	47	50		50	47

TNM, tumor–node–metastasis; LNM, lymph node metastasis