Table 3.

Diagnostic accuracy of clinical criteria to discriminate the presence of a raised ICP in subgroups of patients with isolated head injury (n=92) and code red patients (n=53)

	Sensitivity	Specificity	LR+	LR−	AUC
Isolated TBI
Fixed pupils>5 mm or (HR <60 and SBP >160)	38.3 (24.5–53.6)	95.7 (85.2–99.5)	8.8 (2.2–35.8]	0.7 (0.5–0.8)	0.66 (0.54–0.77)
Code red
Fixed pupils>5 mm or (HR <60 and SBP >160)	53.8 (25.1–80.8)	95.0 (83.1–99.4)	10.8 (2.6–45.5)	0.5 (0.3–0.9)	0.74 (0.56–92)
Fixed pupils>5 mm or (HR <70 and SBP >130)	61.5 (31.6–86.2)	87.5 (73.2–95.8)	4.9 (2.0–12.4)	0.4 (0.2–0.9)	0.75 (0.57–0.92)

AUC, Area Under the Curve; HR, heart rate; LR+, positive likelihood ratio; LR−, negative likelihood ratio; SBP, systolic blood pressure.